Development of mathematical model for lower urinary tract dysfunctions

Abstract: The main objective of this paper is to simulate different types of diseases that cause deformities which occur in the lower urinary tract system together with abnormal micturition , which results from these diseases. To achieve this a modified version of the normal micturition process model proposed by William Fletcher [1] was developed and simulated using MATLAB. The new model is assuming abnormal nerve signals and bladder, ureteral muscles disorders The newly developed model allows to simulate six types of lower urinary tract system (LUTS) disorders caused by dysfunctions in bladder, urethral muscles and nerves control system and gives mathematical representation for abnormal micturition process.
Moreover, the simulation developed has got a wide number of advantages in the medical sector such as design intelligent control scheme to correct any deformations that occur in lower urinary tract system, and can be allowed to test the system safely before trial with humans.

Keywords: lower urinary tract system (LUTS) disorders, Abnormal micturition , Bladder Output Relation(BOR), Urethral Resistance Relation (URR) .